Most nootropics work by affecting neurotransmitters in your brain like acetylcholine, glutamate, serotonin and dopamine. Neurotransmitters are chemicals that act as information messengers between your brain’s nerve cells, which are called neurons. It is neurotransmitters that give the signals to your brain to tell your heart to beat, and your lungs to breathe, but they also play a crucial role in your cognitive function too.By altering these neurotransmitters, nootropics can be used to your advantage by improving the way that your brain functions. Some nootropics also act as vasodilators, which work by boosting the flow of blood and oxygen to your brain, and others by stimulating nerve growth in the brain. But all of them have the same cognitive-enhancing effect.
Nootropics are non-toxic and side effects are extremely rare. They are suitable for everyday use over an extended period of time, and, despite being labeled smart ‘drugs’, they are perfectly safe and legal to take.There have been countless studies proving the cognitive-enhancing effects that nootropics can have, which has led to nootropics being used for many years by doctors to help treat various conditions relating to the brain such as Huntington’s disease, Alzheimer’s and ADHD. When you consider what these kind of drugs are capable of, it becomes obvious why they are used for such diseases. But those who aren’t suffering from these conditions can still take the drugs and achieve positive enhancements such as better coordination, mood enhancement, increased learning and memory abilities, reduced symptoms of depression and stress, and increased attention and motivation. Everyone’s brain chemistry is different, so not everyone will experience the same effects with the same dosage, but the most important thing to realise is that this is not some “pie in the sky” idea. Nootropics do work and can give you a huge number of benefits.
It takes just two capsules and as little as 30 minutes to enter a realm of mental clarity and enhanced focus. In this heightened mental state, your reactions are faster, your focus clearer, your awareness heightened. You’re more productive, more efficient, and your mind is sharper. You can push the limits and transcend the boundaries between success and failure. There are no limitations. The possibilities are endless. Designed by top neuroscientists, NooCube uses the purest, safest, and most powerful ingredients available to safely and effectively improve your cognitive functioning. Every ingredient has been rigorously tested for safety and is supported by decades of clinical research proving their effectiveness at increasing brain function. Many of these ingredients have demonstrated such positive benefits on cognitive function they have even been considered potential treatments for debilitating brain diseases such as Alzheimer’s and dementia. And while caffeine might be the most commonly used nootropic in the world, unlike other nootropic supplements, you won’t find any in NooCube. Why? Caffeine is a powerful stimulant which is great for helping you feel alert, but it does very little to get you into a productive state of mind. Besides, we’d rather you enjoy all the benefits of NooCube without the anxiety or jitters that caffeine can give you.
The NooCube formula contains seven powerful ingredients designed to safely and quickly improve your cognitive functioning. How do we know they work? Take a look below at all the studies and trials backing each ingredient and you’ll see for yourself!
Alpha Glycerylphosphorylcholine (Alpha GPC) is thought to increase levels of acetylcholine in the brain. Acetylcholine is a neurotransmitter – chemical messengers that communicate between brain cells. It is important for memory, learning and concentration, which is why it is known as the learning neurotransmitter. Alpha GPC has demonstrated such a strong ability to improve cognitive function, it is considered a possible treatment for Alzheimer’s disease. In a 2013 study, Alzheimer’s patients given alpha GPC three times daily for 180 days demonstrated consistent improvements in cognitive function test scores, compared to those taking a placebo, who saw no change1. In another study, people with dementia given alpha GPC showed a ‘definite symptomatic improvement’ in psychometric tests after taking alpha GPC for 90 days.
An extract from the Chinese club moss plant, Huperzine-A is an acetylcholinesterase (AChE) inhibitor. AChE breaks down the learning neurotransmitter acetylcholine. By preventing acetylcholine levels from decreasing, Huperzine A creates a surplus of acetylcholine, which can lead to improved mental clarity, concentration and memory. There are countless studies supporting the role of Huperzine in enhancing cognitive function and improving memory, most notably in relation to Alzheimer’s disease. In a 1999 study, young adolescents given huperzine for 4 weeks demonstrated improved learning and memory performance compared to those taking a placebo3. And in one of many studies on huperzine and patients with Alzheimer’s, 58% of patients treated with huperzine showed improved memory4, suggesting that huperzine could also have potential use for treating Alzheimer’s.
Derived naturally from Uncaria tomentosa, a vine that grows in the Amazon rainforest, Cat’s Claw is believed to have neuroprotective benefits. It contains antioxidants, and can help improve your brain health and cognitive performance. One study investigating the antioxidant and neuroprotective ability of Cat’s Claw found it was able to destroy different types of free radicals and protect against cell damage. The researchers determined that Cat’s Claw could be used as possible prevention against Parkinson’s disease.
The indian herb Bacopa monnieri contains compounds called bacosides which are thought to help repair damaged neurons and promote new nerve growth. This improves neuron communication with the brain, helping improve your cognitive function and mental performance. This protective effect on neurons and nerves is why bacopa is yet another of NooCube’s ingredients that has drawn interest over its potential as a dementia and Alzheimer’s treatment, and numerous studies have demonstrated its positive effects on cognitive function and age related cognitive decline. In a 2005 Australian study, people taking a daily 300mg extract of Bacopa monnieri showed a significant improvement in memory tests after 12 weeks than those taking a placebo6. Bacopa was also shown to have a significant effect on memory retention in a similar, placebo controlled study of 76 adults in 20027. And another study in 2008 showed that 12 week supplementation with Bacopi resulted in improved scores on a variety of cognitive assessments in elderly participants.
Also known as Avena sativa, Oat Straw comes from wild green oats and has been used as a brain booster in folk medicine since the Middle Ages. Oat straw is believed to work by increasing alpha-2 waves in the brain – which are highly active during periods of wakefulness – as well as controlling inflammation within artery walls. This increases blood flow to the brain, helping you feel more awake and alert. A 2015 study gave volunteers either a placebo or 800mg green-oat extract (GOE) each day for six days and assessed their cognitive function with a range of computerised tasks. Those taking GOA were able to complete timed tasks faster and also performed better in memory tasks9. Another study gave weekly doses of oat herb extract to elderly participants with below-average cognitive performance, after which they then performed significantly better on a test designed to measure attention, concentration and the ability to maintain task focus.
L-THEANINE & L-TYROSINE
Found in green and black tea, L-theanine is an amino acid that can help relieve stress while stimulating neurotransmitters in the brain, creating a relaxed but alert feeling. L-tyrosine, another amino acid, is involved in the manufacture of dopamine and noradrenaline; neurotransmitters that play a key role in mental alertness and focus, particularly in stressful situations. As a result, L-tyrosine is thought to help improve cognitive performance by reducing the effects of stress and fatigue on performance and making it easier to remain focused. A 2011 study showed that both attention and memory in volunteers significantly improved after they were given l-theanine and green tea extract for 16 weeks11. Another study investigating the effects of l-tyrosine on cognitive function found it improved cognitive flexibility (the brain’s ability to switch between thinking about one concept to another) when compared to a placebo.